Multiple pathways of human exposure to poly- and perfluoroalkyl substances (PFASs): From external exposure to human blood

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Can profiles of poly- and Perfluoroalkyl substances (PFASs) in human serum provide information on major exposure sources?

BACKGROUND Humans are exposed to poly- and perfluoroalkyl substances (PFASs) from diverse sources and this has been associated with negative health impacts. Advances in analytical methods have enabled routine detection of more than 15 PFASs in human sera, allowing better profiling of PFAS exposures. The composition of PFASs in human sera reflects the complexity of exposure sources but source id...

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Author’s response to reviews Title: Can Profiles of Poly- and Perfluoroalkyl Substances (PFASs) in Human Serum Provide Information on Major Exposure Sources? Authors:

Title: Can Profiles of Polyand Perfluoroalkyl Substances (PFASs) in Human Serum Provide Information on Major Exposure Sources? Authors: Xindi Hu ([email protected]) Clifton Dassuncao ([email protected]) Xianming Zhang ([email protected]) Philippe Grandjean ([email protected]) Pál Weihe ([email protected]) Glenys Webster ([email protected]) Flemming Nielsen ([email protected]....

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Early-Life Exposure to Perfluoroalkyl Substances and Childhood Metabolic Function

BACKGROUND Perfluoroalkyl substances (PFASs) are synthetic chemicals that may persist in the environment and in humans. There is a possible association between early-life PFAS exposure and metabolic dysfunction in later life, but data are limited. METHODS We studied 665 mother-child pairs in Project Viva, a Boston, Massachusetts-area cohort recruited 1999-2002. We quantified concentrations of...

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Prenatal Exposure to Perfluoroalkyl Substances and Behavioral Development in Children

BACKGROUND In recent years, prevalence rates of behavioral disorders in children have increased. One factor possibly implied in the etiology of behavioral disorders is exposure to perfluoroalkyl substances (PFASs). The use of PFASs is highly integrated into everyday life, and exposure is ubiquitous. Exposure to PFASs during early life may be particularly harmful, as it represents a critical tim...

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Human dietary exposure to perfluoroalkyl substances in Catalonia, Spain. Temporal trend.

In this study, we assessed the levels of 18 perfluoroalkyl substances (PFASs) in the most widely consumed foodstuffs in Catalonia, Spain, as well as the total dietary intake of these compounds. Forty food items were analysed. Only perfluoropentanoic acid (PFPeA), perfluorohexadecanoic acid (PFHxDA) and perfluorooctanoicdecanoic acid (PFOcDA) were not detected in any sample. Perfluorooctane sulf...

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ژورنال

عنوان ژورنال: Environment International

سال: 2020

ISSN: 0160-4120

DOI: 10.1016/j.envint.2019.105244